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This study proposes a novel elemental composition modeling framework for constructing high-fidelity anthropomorphic phantoms, addressing the critical bottleneck of clinical data scarcity in medical imaging research.

High–linear energy transfer (LET) alpha-particle radiotherapy (RT) produces dense ionization tracks that generate complex DNA damage and may induce potent immunostimulatory signals. We compared alpha‑particle and photon RT across...

Preclinical glioblastoma (GBM) models are crucial for the development of novel therapeutic strategies to improve GBM outcomes. Highly conformal conventional fractionation forms the basis for standard-of-care radiotherapy (RT) in...