Cherenkov imaging enables non-invasive, real-time visualization of superficial dose during radiation therapy. In TSET using the Stanford standing technique, dose uniformity is highly sensitive to daily patient positioning. This s...
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424 entries curated across talks and posters.
To refine the photochemical dose–response relationship for single-fraction Photofrin-mediated PDT by relating modeled reacted singlet oxygen dose to long-term tumor control and by using multispectral singlet oxygen luminescence d...
Sentinel lymph node biopsy (SLNB) in melanoma utilizes preoperative lymphoscintigraphy +/- SPECT/CT for accurate identification of draining lymph nodes for surgical planning. However, SPECT/CT imaging is time consuming and is oft...
Water calorimetry enables measurement of absolute absorbed dose to water, but its practical implementation depends strongly on vessel design and adequate isolation of the sensitive volume. This work presents the development and i...
To integrate the first nozzle-mounted, quad-camera prompt gamma imaging (PGI) system on a clinical proton therapy gantry and to evaluate its efficacy for proton range verification under realistic treatment delivery conditions.
The clinical translation of ultra-high dose rate (FLASH) radiotherapy is hindered by an incomplete understanding of the physical parameter space required to optimize normal tissue sparing. This study utilizes a human bone marrow-...
Conventional radiomics models often treat tumors as spatially homogeneous entities, limiting their ability to capture intratumoral heterogeneity and its impact on prognosis and treatment resistance. Habitat imaging addresses this...
To evaluate CT-derived longitudinal changes in regional lung function following definitive treatment with photon versus proton radiotherapy in patients with locally advanced non-small cell lung cancer (LA-NSCLC).
Recent advances in nanophotonic engineering have enabled subwavelength nanostructures to be patterned onto conventional scintillating materials, significantly enhancing light yield by both amplifying and directing emission toward...
Functional lung avoidance radiation therapy (FLART) uses pre-treatment ventilation imaging to spare high-functioning lung from radiation. The FLAIR trial, the first randomized controlled trial of this approach, found no quality-o...
To predict the occurrence of clinically significant radiation pneumonitis in lung cancer patients using Raman spectroscopy on pre-treatment plasma samples.
Limiting contralateral breast dose (CBD) is an important concern in breast radiotherapy, as prior studies link doses >1Gy to significantly increased secondary cancer risk. Furthermore, complex beam geometry increases low-dose irr...
We investigate the feasibility of using daily setup free-breathing cone-beam CT (CBCT) as a functional imaging modality to generate longitudinal ventilation maps throughout the treatment course, with the goal of detecting emergin...
In kV x-ray dosimetry, experimental spectral data can be used to benchmark Monte Carlo simulations and, if the experimental is suitably constrained, test the underlying interaction cross-section models used. This project aims to...
To develop a global database of medical physics initiatives in support of a sustainable and equitable collaborative ecosystem that minimizes resource duplication and inefficiencies across stakeholders.
Coronary artery (CA) calcifications (CACs) connect upstream cardiovascular risks with downstream radiotherapy planning decisions, yet these powerful imaging biomarkers are underutilized in radiation oncology. We developed and val...
Organ‑level breast dosimetry is essential for developing robust dose-response models of subsequent breast cancer (SBC) risk in female childhood cancer survivors. Historically, epidemiologic studies relied on surrogate metrics suc...
Only 16% of therapeutic radiation incidents reported nationally to RO-ILS meet “excellent” RO-HAC narrative standards, limiting system learning. Capturing essential context is difficult for time-constrained clinicians, and critic...
To develop an approach for deriving myocardial perfusion maps directly from multi-phase coronary CT angiography (CTA), eliminating the need for dedicated cardiac CT perfusion (CTP) protocols.
Estimating Cervical cancer α/β values from patient local control data and three methods of radiobiological parameter estimation.
Regulatory inspections for multi-site radiation oncology programs are traditionally resource-intensive, requiring approximately 1.0 hour/linac of on-site review. This study quantifies the impact of a centralized, cloud-based gove...
Glioblastoma has a low median survival of 3cm from the tumor, where deformation is minimal. Vessels 80% of patients. Future work will incorporate this pathway into a full front-to-end deformable registration approach to precisely...
Xerostomia is a common toxicity after radical head and neck cancer (HNC) radiotherapy (RT), causing long-term quality-of-life impairment. Although salivary function may recover, dose–response relationships governing long-term rec...
Understanding of medical physics is essential for safe and effective radiation oncology practice. This study evaluates current instructional practices for physics education in radiation oncology physician residency programs follo...