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Proton dose distributions can be very sensitive to setup and anatomical variations. Specifically, back tissue correspondence in posterior beam spine SBRT and changes in lung density or pleural effusion in lung SBRT are scenarios...

Mechanistic tumor growth models provide a framework for linking observed tumor kinetics to underlying biological processes; however, their application to real preclinical datasets is limited by incomplete longitudinal measurement...

To develop a data-efficient, unsupervised deep learning framework for deformable SPECT/CT registration that supports voxel-based dosimetry in radionuclide therapy, particularly in clinical settings with limited imaging datasets.