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Hybrid tangential breast radiotherapy commonly uses a high proportion of open fields to enhance robustness against inter-fraction anatomical variation, potentially limiting planning flexibility. In five-fraction hypofractionated...

In MR-only radiotherapy planning (MROP), limited field-of-view (LFOV) acquisition and imaging artifacts can introduce truncated anatomy and density inaccuracies, reducing the reliability of dose calculation and preventing compreh...

Tumor heterogeneity within and across tumors contributes to variable therapeutic response by altering biophysical transport barriers in the tumor microenvironment (TME). Elevated interstitial fluid pressure (IFP) and reduced hydr...