All conference submissions

To present IAEA- determined photon beam quality correction factors kQ for the IBA FC65-G and PTW 30013 Farmer-type ionization chambers and compare them with the tabulated values in IAEA TRS 398 (Rev.1).

Pin-ridge filters (pRFs) have emerged as a promising hardware-based approach for ultrafast proton beam delivery through upstream proton fluence modulation. While pRF-based planning techniques having been explored computationally,...

Deep-learning (DL) auto-segmentation may improve efficiency in head-and-neck (HN) planning, but clinical use depends on how consistently experts judge contour acceptability and how performance varies by organ. We evaluated a DL-b...

Although consolidative immunotherapy following radiotherapy is standard for locally advanced non-small cell lung cancer (NSCLC), this combination increases the risk of ≥ Grade 2 symptomatic pneumonia (SP). This study utilized an...

To develop an explainable deep learning framework for histological segmentation and prognostic modeling of neuroendocrine tumors (NET) liver metastasis, comparing the efficacy of non-linear deep survival analysis against traditio...

A novel targeted alpha-particle therapy (TAT), 225Ac-MTI-201, targets the melanocortin 1 receptor (MC1R) which is highly expressed in metastatic uveal melanoma (MUM) and is currently in a first-in-human clinical trial. The favora...

Radiotherapy is a standard treatment for lung cancer, yet 40%–50% of patients develop local failure or recurrence, largely due to radioresistance. Proton beams, characterized by the Bragg peak and higher relative biological effec...

Accurate radiation documentation is essential for assessing patient risk during fluoroscopically guided procedures. Radiation Dose sheets are commonly used but may omit exposure details while DICOM Radiation-Dose-Structured-Repor...

To evaluate longitudinal changes in structural MRI biomarkers across three radiotherapy timepoints in advanced cervical cancer and their association with treatment response and recurrence.

CT ventilation imaging (CTVI) is a promising functional imaging modality. However, conventional 3D approaches using Displacement Vector Fields (DVF) assume a linear trajectory between peak-exhale and peak-inhale phases, potential...

Proton therapy’s ability to spare normal tissue generally lowers complications, making it an attractive treatment option for head and neck (HN) cancer. Yet, oral mucositis, one of the most frequent and clinically relevant toxicit...

Proton PBS treatment planning relies on iterative numerical optimization and is time-consuming. Deep learning enables rapid inference and therefore has the potential for fast prediction of beamlet intensities from anatomical imag...

Proton range uncertainty limits the precision of proton therapy. While PET-based verification is promising,current modeling methods are computationally inefficiency. This study presents a fast, accurate approach for simultaneous...

Convolution/superposition is a widely-used method for radiotherapy dose calculation, in which energy deposited at the first interaction point (TERMA) is convolved with a scatter kernel to obtain the dose. To account for tissue he...

Quantitative PET imaging biomarkers such as metabolic tumor volume (MTV) and maximum standardized uptake value (SUVmax) have demonstrated prognostic value in lymphoma; however, these metrics fail to characterize intratumor hetero...

The MIRAGE trial demonstrated reduced acute toxicity in intact prostate radiotherapy in MRI arm, partially attributed to the use of smaller PTV margins (2 mm versus 4 mm with CT guidance). Motivated by these findings, this study...

HyperSight cone-beam CT (HS-CBCT) on C-arm linacs may enable CBCT-based replanning by improving image quality, HU fidelity, and field-of-view (FOV). We evaluated clinical feasibility and dose-recalculation agreement using patient...

The primary objective of this study was to develop a generalized deep learning-based dose calculation engine capable of accurate, site-independent dose prediction. By utilizing a beamlet-based input strategy, we aimed to establis...

To evaluate a high-resolution CMOS 2D detector array (myQA SRS, IBA GmbH, Germany) as an efficient alternative to radiochromic films (RCF) for IMRT commissioning.

To develop a cost-effective, open-source system for patient-specific voluntary breath-hold (VBH) during CT simulation. The goal is to provide accurate gating thresholds for LINAC systems, such as Varian Truebeam Real-time Positio...

PET imaging of positrons emitted during megavoltage radiotherapy has not been implemented due to concern of high-count rates. This computational study explores the feasibility of coincidence-counting experiments using two scintil...

While reinforcement-learning (RL) based needle placement optimization has been explored in prostate brachytherapy, its application to gynecologic high dose rate (HDR) brachytherapy remains limited. This work presents a reinforcem...

The RefleXion X1 system requires activity concentration (AC) >5 kBq/mL for successful biology-guided radiotherapy (BgRT). We evaluated whether the extended field-of-view (FOV) PET detector in a can lower this AC threshold and exp...

Neoadjuvant chemoradiotherapy (nCRT) improves local control in patients with locally advanced rectal cancer (LARC); however, substantial heterogeneity exists in postoperative recurrence risk. This study aimed to evaluate the feas...