Institution profile

QST Hospital

Rank #292 · 3 unique linked submissions.

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Hiroaki Ikawa, PhD 2 Taku Nakaji, PhD 2 Makoto Shinoto, MD, PhD 2 Masashi Koto, MD, PhD 1
Poster Poster Program
LETd Escalation Using Scanned Neon (20Ne) Ion Therapy for Radioresistant Tumors

Neon ions (²⁰Ne) offer substantially higher clinically achievable dose-averaged linear energy transfer (LETd) escalation in the target compared to protons or carbon ions. LETd escalation has the potential to enhance biological effectiveness against radio-resi...

Taku Nakaji, PhD
Therapy Physics
Paper Proffered Program
The First Multi-Ion Therapy for Head and Neck Cancers: Planning Protocol, Plan Robustness, and Biological Rationale for a Phase I Clinical Trial

To establish the treatment planning protocol and evaluate the biological rationale for the world’s first dose-averaged LET (LETd)-optimized multi-ion therapy program for head and neck cancers. This study characterizes the plan robustness and potential therape...

Hiroaki Ikawa, PhDMakoto Shinoto, MD, PhDTaku Nakaji, PhD
Therapy Physics
Paper Proffered Program
Parametric Imaging of Washout In Range‑Verification Open PET: Clinical Demonstration of Tumor Diagnosis during Carbon‑Ion Therapy

Tumor oxygenation plays a critical role in treatment response and progression. However, repeating PET with hypoxia-specific radioligands at every treatment fraction is not practical. Tumor-vascular status, by contrast, can be assessed by measuring the washout...

Masashi Koto, MD, PhDHiroaki Ikawa, PhDMakoto Shinoto, MD, PhD
Therapy Physics