In head-and-neck radiotherapy, relatively large planning target volume (PTV) margins of 5-mm are standardly used to account for setup uncertainty and anatomical variations. However, this comes at the expense of increased dose to nearby structures, resulting i...
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London Health Sciences Center
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Stereotactic body radiotherapy (SBRT) plays a central role in the management of early-stage and oligometastatic lung cancer. Over recent years, there has been significant interest in automating treatment planning through the development of knowledge-based pla...
Definitive radiotherapy for oropharyngeal cancer (OPC) requires adequate PTV coverage, but the optimal degree of target coverage is unknown. Some protocols require a PTVD95≥95% whereas others require PTVD95≥100% of prescription dose. Prescribing higher PTV do...
To characterize the dependence of relative electron density (RED) to Hounsfield unit (HU) calibration accuracy on acquisition and reconstruction settings on the Varian Ethos HyperSight CBCT to assess implications for adaptive radiotherapy dose calculation.
We previously developed a system capable of acquiring accurate transrectal 3D micro-ultrasound (mUS) images to allow for visualization and focal treatment of intra-prostatic lesions during prostate brachytherapy. This system made use of a mUS probe with non-s...
Therapy Physics