David Palma, MD/PhD

In head-and-neck radiotherapy, relatively large planning target volume (PTV) margins of 5-mm are standardly used to account for setup uncertainty and anatomical variations. However, this comes at the expense of increased dose to nearby structures, resulting i...

Definitive radiotherapy for oropharyngeal cancer (OPC) requires adequate PTV coverage, but the optimal degree of target coverage is unknown. Some protocols require a PTVD95≥95% whereas others require PTVD95≥100% of prescription dose. Prescribing higher PTV do...