Organ‑level breast dosimetry is essential for developing robust dose-response models of subsequent breast cancer (SBC) risk in female childhood cancer survivors. Historically, epidemiologic studies relied on surrogate metrics such as prescription dose due to...
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National Cancer Institute
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The Russian invasion of Ukraine has significantly disrupted radiation therapy (RT) services, highlighting the urgent need to replace Cobalt-60 machines and modernize infrastructure and training across 43 RT centers. In response, Help Ukraine Group (HUG) and R...
Amid ongoing war, Ukraine continues to maintain and modernize radiation therapy (RT) services. Between 2023 and 2025, 24 linacs were installed to replace aging, non-rechargeable cobalt units. While linacs offer clinical advantages, they require stringent dosi...
To evaluate sensitive organ and fetal doses for women undergoing mammography exams to determine potential risk and any justification for shielding.
To quantify the impact of proton dose calculation methodology, including nuclear halo contributions, on secondary cancer risk for near-field organs following proton craniospinal irradiation.
The NCI Pediatric Proton and Photon Therapy Comparison Cohort aims to compare the risk of second malignancies in patients treated with proton versus photon radiotherapy. Using Monte Carlo (MC) simulations, normal tissue dose estimates were retrospectively cal...
To develop a machine learning–based method for rapid estimation of patient-specific organ doses in fluoroscopically guided procedures.
A multi-institution study is underway to characterize the organ doses received by adult patients undergoing ten common types of fluoroscopically guided interventional (FGI) procedures in the United States. Unlike diagnostic procedures, FGI are not standardize...
Pediatric dose from CT remains a concern, and recent evidence from radiotherapy has increased interest in dose to specific cardiac substructures (e.g., the left anterior descending coronary artery). Pediatric whole-body phantoms that contain detailed cardiac...