Organ‑level breast dosimetry is essential for developing robust dose-response models of subsequent breast cancer (SBC) risk in female childhood cancer survivors. Historically, epidemiologic studies relied on surrogate metrics such as prescription dose due to...
Author profile
Choonsik Lee, PhD
Division of Cancer Epidemiology and Genetics, National Cancer Institute
To quantify the impact of proton dose calculation methodology, including nuclear halo contributions, on secondary cancer risk for near-field organs following proton craniospinal irradiation.
The NCI Pediatric Proton and Photon Therapy Comparison Cohort aims to compare the risk of second malignancies in patients treated with proton versus photon radiotherapy. Using Monte Carlo (MC) simulations, normal tissue dose estimates were retrospectively cal...
To develop a machine learning–based method for rapid estimation of patient-specific organ doses in fluoroscopically guided procedures.
A multi-institution study is underway to characterize the organ doses received by adult patients undergoing ten common types of fluoroscopically guided interventional (FGI) procedures in the United States. Unlike diagnostic procedures, FGI are not standardize...
Pediatric dose from CT remains a concern, and recent evidence from radiotherapy has increased interest in dose to specific cardiac substructures (e.g., the left anterior descending coronary artery). Pediatric whole-body phantoms that contain detailed cardiac...