Automatic intensity-based CBCT registration for initial spine treatment setup is challenging due to the similar appearance of vertebral bodies (VBs), which can lead to misalignment. This study evaluated the feasibility of using AI-based VB auto-contouring as...
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Corewell Health William Beaumont University Hospital
Rank #90 · 11 unique linked submissions.
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To design and validate reliable treatment planning and delivery verification methods for TMPRT in the phase III NRG CC-017 trial, which compares TMPRT to standard radiotherapy in adults with newly diagnosed MGMT-unmethylated glioblastomas, with these methods...
Maintaining a full bladder during prostate radiotherapy helps reduce bladder toxicity, but drinking before treatment leads to continuous bladder filling during adaptive planning, potentially displacing the prostate. This study characterizes bladder filling ki...
This study aims to develop the first 4pi dynamic proton arc optimization algorithm which searches for efficient arc trajectories in 4pi space, explores the potential dosimetric improvements in multiple disease sites. Then we demonstrate its feasibility throug...
Spot-scanning proton arc (SPArc) therapy combines the physical advantages of proton therapy with continuous arc delivery. However, most current SPArc planning approaches assume static beam delivery and do not account for the synchrocyclotron-based proton ther...
To evaluate the robustness of spot-scanning proton arc therapy (SPArc) to stochastic spot-wise monitor unit (MU) delivery errors.
This study assessed the impact of machine-specific delivery sequence in quantifying interplay effects for lung stereotactic body radiotherapy (SBRT) between two proton therapy modalities, intensity-modulated proton therapy (IMPT) and spot-scanning proton arc...
This study aims to introduce a new SPArc algorithm with a variable tolerance window (SPArc-variable) to further improve plan quality for patients receiving bilateral breast and regional nodal irradiation, by allowing extra energy layers across specific arc tr...
To compare the repeatability of quantitative dynamic contrast enhanced (DCE) MRI with the reference region model (RRM) against the conventional Tofts model and to test if it can be improved using the two-step Constrained RRM (CRRM).
Spot-scanning proton arc therapy(SPArc) delivers pencil beam scanning dose during continuous gantry rotation and its dosimetry depends on the underlying beam model particularly lateral spot size. This study evaluated the impact of spot size on SPArc plan qual...
This study aimed to develop a novel optimization framework for spot-scanning proton arc therapy (SPArc) to simultaneously achieve highly uniform beam delivery time (BDT) across control points, improved delivery efficiency, and optimal dose distribution.