Contrast-enhanced single-energy CT (SECT) scans provide superior image contrast and better differentiation of the target volume and vascular structures compared to non-contrast CT scans at the cost of deteriorated dose calculation due to the high density of t...
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Siemens Healthineers
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Quantitative Digital Subtraction Angiography (qDSA) is a method for determining blood velocity in which iodinated contrast agent is injected into pulsatile arterial blood flow and oscillations in contrast are tracked as they propagate downstream. qDSA aims to...
Radiotherapy dose calculation is typically based on a computed tomography (CT) scan and requires a conversion of CT numbers to the relevant physical parameter, mass density (MD) or relative electron density (RED) for photon therapy, and stopping-power ratio (...
To evaluate the performance of a 2D markerless spine position monitoring technique for Auto Beam Hold based on kilovoltage triggered imaging.
To evaluate the clinical accuracy and utility of a commercial deep learning-based auto-segmentation tool by Siemens for delineating brain metastases (GTV) and organs-at-risk (OAR) on contrast-enhanced MRI.
Monte Carlo simulations are widely used to derive effective dose conversion factors (k-factors) for CT; however, acquisition parameters such as helical pitch and tube starting angle are often randomly selected. The impact of these parameters on the variabilit...
Tin filtration has shown improved dose efficiencies in conventional CT for renal stone imaging. Photon-counting CT (PCCT) enables virtual monoenergetic image (VMI) reconstructions that can enhance stone conspicuity. This study evaluates potential dose-efficie...
High-pitch dual-source acquisition (“FLASH”) with tin spectral filtration has substantially reduced radiation dose while minimizing patient motion, both of which are particularly important for pediatric imaging. However, in adults, tin-filtered spectra have b...
Photon-counting-detector (PCD) CT acquires multi-energy data in a single scan, enabling quantitation of electron density (ρe) and effective atomic number (Zeff). This study assessed the performance of PCD-CT for ρe and Zeff mapping across different phantom si...
In investigating image-based lung ventilation, a fundamental question must be answered: is the measurement technique repeatable? Repeatability of ventilation imaging in PET and CT have been studied, but MRI is emerging. Crucial to deriving ventilation is the...
The efficacy of stereotactic radiosurgery (SRS) and radiotherapy (SRT) for brain metastases is often compromised by tumor growth and soft tissue changes between simulation and treatment. To eliminate these latencies, we clinically implemented a novel same-day...
Stopping-power ratio (SPR) is used in proton therapy to calculate the radiation dose distributions. SPR depends on tissue composition and can be calculated using multi-energy CT. This study compares the accuracy of SPR calculated using energy-integrating dete...
AGuIX nanoparticles, composed of a polysiloxane core with gadolinium chelates, are a theranostic agent, providing both MRI contrast and radiosensitization. The ongoing NanoBrainMets clinical trial looks to evaluate the therapeutic efficacy of AGuIX by quantif...
Recent advances in MRI could offer patients with benign lung disease whole-lung ventilation mapping that may serve as a surrogate for pathophysiological changes such as increased airway resistance and decreased lung compliance. Ventilation maps can be derived...