Moffitt Cancer Center

To assess the effectiveness of SVD-based denoising on the brain Diffusion Weighted images acquired from a 0.35T ViewRay Magnetic Resonance Linac (MRL) and enhance the image quality while preserving the diffusion information.

Standard image-guided radiotherapy(IGRT) approaches for muscle invasive bladder cancer(MIBC) require large target margins due to bladder fill variability, inevitably resulting in increased organ-at-risk(OAR) doses and toxicity risk. CBCT-guided online adaptiv...

Cherenkov radiation imaging has become an increasingly more common imaging modality as a real-time beam delivery visualization aid with potential for dosimetry. Dosimetric studies require a comprehensive analysis of factors which affect the optical photon gen...

Radiopharmaceuticals, Theranostics, and Nuclear Medicine

Lung function requires a close interaction between pulmonary circulation, the respiratory pump, and lung parenchyma. Diseases of the respiratory system can impact each of these components, therefore differentiation between the individual components and contri...

The American Association of Physicists in Medicine has sponsored two summer undergraduate research programs since 2001: the Summer Undergraduate Fellowship Program (SUFP) and the Diversity Recruitment through Education and Mentoring Program (DREAM) programs....

Stark global inequities persist in access to radiological health services, with low- and middle-income countries (LMICs) bearing an increasing cancer burden while facing critical shortages in trained medical physicists and radiation oncologists. Virtual educa...

TH- Brachytherapy

While hypofractionation and dose escalation may provide enhanced tumor control in locally advanced lung cancer, previous attempts generally increase toxicity (e.g., esophagitis and/or pneumonitis). We present an approach leveraging CBCT-guided online adaptive...

Previous studies in predicting the risk of urgent care visits for non-small-cell lung cancer (NSCLC) patients receiving combined modality therapy (CMT) have generally focused on pre-treatment risk factors. Our study aimed to develop a risk prediction model wi...

A novel targeted alpha-particle therapy (TAT), 225Ac-MTI-201, targets the melanocortin 1 receptor (MC1R) which is highly expressed in metastatic uveal melanoma (MUM) and is currently in a first-in-human clinical trial. The favorable qualities of TAT include t...

Ensuring precise delivery of radiotherapy is paramount, especially in high dose rate settings where small deviations can create large, unplanned doses, jeopardizing patient safety and treatment outcome. Current dosimetry and QA methods operate on signals anal...

Many cancer studies concentrate in isolated markers like oxygenation, pH or relaxivity measurements. We believe studying all biomarkers and its interactions as microenvironments is the key. The goal of our study is to build a library of multi-parametric data...

Ionizing radiation acoustic imaging (iRAI) is a noninvasive technique for monitoring radiation delivery. Although iRAI acquisition during irradiation has been demonstrated, its use to quantify spatial dose variations alongside biological measurements under FL...

Glomerular Filtration Rate (GFR) is the most useful clinical indicator of renal function for staging kidney disease, adjustment of drug dosages, and screening for X-ray contrast administration. GFR may be estimated via plasma and/or urinary methods (eGFR) usi...

Professional

Mentorship is widely accepted to contribute to academic productivity and career development. We aim to develop a national cross-sectional survey study distributed to therapeutic and diagnostic imaging medical physics residency programs to gain insight into th...

The American College of Radiology (ACR) has long been relied upon by the medical physics community to publish QC guidance that is practical and well-considered. After years of anticipation, the ACR has finally published QC manuals for NM/SPECT (2024) and PET...

The recently published Appropriate Use Criteria for Molecular Breast Imaging (MBI) by an expert workgroup has identified two clinical scenarios where MBI may serve an important role in the management of breast cancer patients: 1) supplemental screening in wom...

At the AAPM 2025 conference, these speakers conducted a 90-minute session titled “Building a Radiopharmaceutical Therapy Program and Expanding to Clinical Trials.” Following the talks and the ten-minute Q&A session, the audience continued to ask questions for...

Therapy Physics

Builds on the AI theme from AAPM's 2025 Annual Meeting while moving from image interpretation to quantitative, treatment-enabling applications. This is an area of growing convergence between SNMMI and AAPM. Focus: How AI and machine learning are transforming...

Nuclear medicine is currently experiencing significant growth, driven largely by the expanding use of radiopharmaceutical therapies. This growth has renewed interest in SPECT/CT system design, particularly the transition from conventional dual-headed NaI-base...

For decades, PET imaging was nearly synonymous with FDG. With improvements in PET technology, investment resulting from the emergence of theranostics, and improvements in reimbursement, the landscape of PET has shifted dramatically in recent years. Brain path...