The spread-out Bragg peak (SOBP) technique uses ridge filters to broaden the depth-dose profile, producing a dose distribution similar to a single-field-uniform(SFU) approach. In contrast, the single-energy pristine Bragg peak(SEPBP) approach relies on range...
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University of Wisconsin School of Medicine and Public Health
Rank #136 · 7 unique linked submissions.
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To propose a clinically relevant, quantitative comparison of low-contrast edge definition on routine CT Head examinations.
To experimentally quantify the mechanical delivery errors of a pre-clinical Dynamical Collimation System (DCS) prototype for intensity modulated proton therapy (IMPT) and evaluate the dosimetric impact of these errors to the target coverage and organ sparing.
While 30% of lung cancer patients cannot tolerate breath-hold, free-breathing(FB) proton pencil-beam-scanning(PBS) deliveries compromise target coverage from the interplay effects of large motion. This study presents a novel FB-gated spirometer-based respirat...
To implement a full abdominal motion model that combines respiration with gastrointestinal (GI) motility and quantify its interplay impact in pencil-beam scanning (PBS) proton therapy.
Dose-optimized proton pencil beam scanning (PBS) treatments that are collimated using the Dynamic Collimation System (DCS) have greater dosimetric sparing of healthy tissue compared to uncollimated treatment plans, but differences in linear energy transfer (L...
To quantify the impact of gastrointestinal (GI) motility on pencil-beam scanning (PBS) proton therapy for abdominal cancers, and assess how fractionation and motion amplitude mitigate motility-induced interplay effects.