Author profile
Department of Radiation Oncology, Dana-Farber Cancer Institute/Brigham and Women’s Hospital, Harvard Medical School
Conventional radiotherapy dose (Gy) quantifies deposited energy, but response is influenced by the local radiochemical environment driving indirect DNA damage. Superoxide is a comparatively long-lived paramagnetic radical species showing potential as a marker...
To evaluate the clinical accuracy and utility of a commercial deep learning-based auto-segmentation tool by Siemens for delineating brain metastases (GTV) and organs-at-risk (OAR) on contrast-enhanced MRI.
To characterize the microsecond-scale dynamics of the free induction decay (FID) of a 0.35T Magnetic Resonance (MR)-guided Linear Accelerator (MR-Linac) during irradiation.
The efficacy of stereotactic radiosurgery (SRS) and radiotherapy (SRT) for brain metastases is often compromised by tumor growth and soft tissue changes between simulation and treatment. To eliminate these latencies, we clinically implemented a novel same-day...
AGuIX nanoparticles, composed of a polysiloxane core with gadolinium chelates, are a theranostic agent, providing both MRI contrast and radiosensitization. The ongoing NanoBrainMets clinical trial looks to evaluate the therapeutic efficacy of AGuIX by quantif...
To evaluate the correlation between lung tumor and pulmonary vessel motion under MR-guided radiotherapy and to inform surrogate tracking feature selection when direct tumor tracking is challenging.
Therapy Physics
Therapy Physics