All conference submissions

Radiotherapy (RT) and photodynamic therapy (PDT) for breast cancer are limited by tumor hypoxia and suboptimal photosensitizer performance.

To develop a clinically oriented framework for patient-specific 3D dose prediction in head-and-neck radiotherapy, emphasizing DVH-consistent performance for target coverage and OAR sparing.

Diffusion-weighted MRI (DWI) and its derived parameters, including apparent diffusion coefficient (ADC) and intravoxel incoherent motion (IVIM) metrics, are valuable for assessing tumor response to radiotherapy. However, DWI proc...

Radiation-induced lymphocyte killing is correlated with worse clinical outcomes in various cancers, including sarcomas. Models to simulate radiation dose delivery to circulating lymphocytes have been developed, and significant co...

To investigate internal treatment margins for targets undergoing cardiorespiratory motion with the use of dynamic tracking technology.

Spot-scanning proton arc (SPArc) therapy combines the physical advantages of proton therapy with continuous arc delivery. However, most current SPArc planning approaches assume static beam delivery and do not account for the sync...

During the implementation of the pilot of the Canadian Association of Radiologists’ (CAR) Lung cancer screening program, our healthcare system had to adapt our existing practices and protocols. Our physicists decided to investiga...

Evaluate our radiosurgical experience with trigeminal neuralgia treatment, with emphasis on short‑term pain relief and the influence of biologically effective dose (BED).

Patients with head and neck (H&N) cancer frequently require percutaneous endoscopic gastrostomy (PEG) tube placement to maintain adequate nutrition during treatment. Current PEG placement decisions are primarily based on patient-...

To evaluate the effectiveness of SpaceOAR in sparing the rectum by calculating the normal tissue complication probability (NTCP) from radiotherapy treatment plans for prostate cancer patients treated with and without a spacer.

Postoperative radiotherapy for cervical cancer involves large target volumes, making it challenging to achieve adequate dose homogeneity while sparing organs at risk (OARs). Multi-arc volumetric modulated arc therapy (VMAT) impro...

To experimentally determine the effective point of measurement (EPOM) shift of an Exradin A1SL ion chamber in kilovoltage x-ray beams (40-250 kVp) using water tank measurements.

Accurate histological subtype classification of pleural mesothelioma (PM) from CT imaging remains challenging due to limited labeled data and substantial morphological variability. Data augmentation is a common strategy used to a...

Spatially fractionated radiotherapy (SFRT) treats bulky tumors by creating heterogeneous dose distributions. Although both photon- and proton-based SFRT are accessible, various definitions of the peak-to-valley dose ratio (PVDR)...

The source size (focal spot) of a photon beam from linacs is known to have effects on the output for small-field dosimetry. This study aims to determine quantitatively the sensitivity of beam field output factors (FOF) as a funct...

Singlet oxygen (SO) is the primary cytotoxic agent in photodynamic therapy (PDT); however, real-time measurement of SO during treatment remains challenging. The purpose of this study is to investigate the dependence of SO signal...

Proton therapy (PT) has demonstrated superior healthy tissue sparing compared to photon radiotherapy for various sites; however, PT systems are expensive, which limits global availability. The dielectric wall accelerator (DWA) is...

To investigate the dependence of tumor metabolism on hyperpolarized (HP) pyruvate concentration, administration order, and time interval in repeated MRI measurements.

Gold nanoparticles (GNPs) are promising radiosensitizing agents for high dose rate brachytherapy (HDR); however, complex treatment delivery for HDR has prohibited systematic evaluation of GNP-induced radiosensitization both in vi...

In non-coplanar SBRT/SRS, efficient high-resolution volumetric imaging under limited-angle non-coplanar CBCT (LA-NC-CBCT) acquisition is critical for avoiding potential collisions while ensuring treatment delivery accuracy. Howev...

To develop and validate a continuous two-dimensional output-factor (OF) model and to identify a measurement strategy that achieves accuracy and efficiency.

The interaction between static magnetic fields and charged particle beams necessitates isolating linacs from the magnetic fields from MRI systems and other sources. In the absence of known sources of strong magnetic fields, it ha...

To eliminate the need for CT scans in abdominal MR-Linac treatments by determining and tabulating organ electron densities (EDs) based on patient age and sex. Resultantly, these results promote simpler workflow, costing less time...

To develop an AI agent framework leveraging large language models (LLMs) for intelligent data extraction and reasoning over radiation oncology data from oncology information systems (OIS) and electronic medical records (EMR), ena...