All conference submissions

Stereotactic radiosurgery (SRS) reirradiation for locally recurrent brain metastases (BM) utilizes rigid image registration (RIR) for cumulative dose estimation to balance dose escalation against the risk of adverse radiation eff...

Brachytherapy dose calculations are commonly based on the AAPM TG-43 formalism, which assumes a homogeneous water medium. Although widely used for HDR and LDR brachytherapy, this assumption inadequately represents dose distributi...

Left-sided breast cancer radiotherapy poses a significant challenge in balancing target coverage with the sparing of critical cardiac substructures. RapidArc Dynamic (RAD) is a novel hybrid technique that integrates the continuou...

CT-based lung ventilation imaging can provide a functional assessment of tumor and normal tissue response to lung stereotactic body radiation therapy (SBRT). The speed of ventilation map generation hinders the clinical adoption o...

Dual-energy CT (DECT) enables material differentiation by exploiting the energy-dependent attenuation characteristics of tissues, which is particularly beneficial for carbon ion therapy. This study systematically evaluated a rece...

Lattice radiotherapy (LRT) produces steep vertex–valley gradients, making 2D gamma-based QA insufficient for clinically relevant 3D dose–volume endpoints. We propose an MRI polymer gel–based 3D DVH verification workflow for VMAT-...

Deep-learning (DL) auto-segmentation is routinely used clinically, yet domain shift and vendor model upgrades can change behavior in non-intuitive ways. We present a regression-testing framework to commission upgraded commercial...

To develop a super-resolution convolutional neural network to generate high-resolution temporal bone images beyond the resolution limitation of a commercial photon-counting-detector (PCD) CT.

Tumor regression during radiotherapy reflects underlying radiosensitivity, yet adaptive radiotherapy is largely guided by geometric changes and physical dose metrics. We developed a biologically adaptive radiation therapy (BART)...

In multi-target Gamma Knife (GK) radiosurgery, the clinical default plan typically sequences shots based on geometric efficiency to minimize treatment duration. However, this approach ignores the time-dependent biological effects...

Dose-volume constraints for organs at risk (OARs) in stereotactic body radiation therapy (SBRT) for thoracic cancer patients have been well established through multiple prospective clinical trials. However, during equivalent dose...

Biological systems are inherently structured, with genes and molecular components interacting through organized pathways and networks. Graph-based representations are therefore widely used in biological analysis. However, many ex...

To investigate the feasibility and potential benefits of biologically optimised treatment planning (BiRT) utilizing heterogeneous focal-boost prescriptions based on patient-specific cell density distributions. This study compares...

The underlying mechanisms of radiation-induced lymphocyte depletion are not fully understood. Our goal is to determine if the observed depletion in circulating lymphocytes after radiotherapy is solely due to cell kill, or if chan...

Maintaining a full bladder during prostate radiotherapy helps reduce bladder toxicity, but drinking before treatment leads to continuous bladder filling during adaptive planning, potentially displacing the prostate. This study ch...

Accurate segmentation of brain metastases (BM) is essential for stereotactic radiosurgery planning and longitudinal assessment, yet manual contouring is time-consuming and subject to substantial inter-observer variability. We dev...

To evaluate the doses to the bone marrow and kidneys from Lu-177 radiopharmaceutical therapy (RPT), as affected by radiopharmaceutical type, cycle of administration, and tumor volume.

Dose Volume Histogram (DVH) indices remain a backbone of treatment planning in radiation therapy. Many outcomes studies treat DVH indices as independent candidate predictors and retain only indices that meet the statistical signi...

Widely used internal dosimetry tools such as OLINDA/EXM and MIRDcalc provide validated implementations of the MIRD schema but are primarily desktop-based, which can limit accessibility, transparency, and extensibility. This work...

To address fragmentation and variability in longitudinal brain lesion assessment, we developed Brain-Dynamics, a vendor-neutral platform integrating auto‑segmentation, multimodal co‑registration, lesion labeling/tracking, and qua...

Non-breathing physiological motions of abdominal organs at risk (OARs) are insufficiently characterized to support understanding of their dosimetric impact and possible need for monitoring. The dynamics of such motions were chara...

To evaluate a hybrid radiotherapy planning technique combining conventional 3D conformal tangential fields with limited VMAT arcs (hybrid 3DCRT–VMAT) for whole‑breast irradiation, and compare its dosimetric performance, organ-at-...

To integrate qualitative assessments from experienced treatment planners with quantitative geometric comparisons to evaluate the clinical utility of a deep learning (DL)-based auto-segmentation tool and establish performance crit...

The Russian invasion of Ukraine has significantly disrupted radiation therapy (RT) services, highlighting the urgent need to replace Cobalt-60 machines and modernize infrastructure and training across 43 RT centers. In response,...