National Cancer Center

Commercial cylindrical applicators used for vaginal brachytherapy may not always ensure sufficient contact with the vaginal mucosa, particularly in patients with reduced tissue compliance, leading to air gaps and dose uncertainty. To address these limitations...

In proton therapy, precise beam range measurement and dose verification are critical to overcome range uncertainty and ensure patient safety. This study developed and evaluated a technique to reconstruct and visualize in vivo dose distribution from spot scann...

This study aimed to develop and evaluate a personalized, geometrically optimized 3DGRID radiotherapy strategy using Helical Tomotherapy (TOMO), designed to maximize tumor ablation while preserving surrounding organs at risk (OARs). We systematically compared...

Differences in biological effects among radiation qualities arise from variations in the spatial distribution of initial DNA damage and subsequent repair processes, both are closely linked to chromatin organizations. This study aimed to integrate recent advan...

This study aimed to develop and evaluate a multi-scale dose-defined lung subregional dosiomics approach for predicting radiation pneumonitis (RP) in lung cancer patients treated with conventionally fractionated VMAT.