Vanderbilt University Medical Center

The radius and spacing of high-dose spheres (HDS) in Lattice Radiotherapy (LRT) used by clinicians varies considerably This study quantifies how changing these parameters impacts dosimetric characteristics (such as peak-to-valley dose ratio (PVDR) and mean do...

Accurate survival prediction following radiation therapy for glioma remains challenging due to heterogeneous tumor biology and treatment response. This study proposes a multimodal framework integrating deep radiomic features from longitudinal MRI, tumor growt...

Accurate estimation of microstructural parameters by Imaging Microstructural Parameters Using Limited Spectrally Edited Diffusion (IMPULSED) diffusion MRI, including cell size and intracellular volume fraction, is promising for monitoring radiation treatment...

To evaluate the accuracy of the Analytical Anisotropic Algorithm (AAA) and Acuros XB (AXB) implemented in the Eclipse treatment planning system for small-field dosimetry in low-density lung, with emphasis on their performance in lung stereotactic body radiati...

The source size (focal spot) of a photon beam from linacs is known to have effects on the output for small-field dosimetry. This study aims to determine quantitatively the sensitivity of beam field output factors (FOF) as a function of field sizes between cir...

Lung stereotactic body radiotherapy (SBRT) is now standard of care for oligometastatic and small pulmonary lesions, where very small radiation fields are used. Although inhomogeneity correction algorithms have been well validated for larger fields, limited da...

To survey current clinical practice, assess priorities, and identify resource gaps related to environmental sustainability in medical imaging physics.

Accurately identifying clinically significant prostate cancer (PCa) lesions remains a difficult task. Although tumor characteristics associated with false-negative lesions have been investigated, the potential radiologist search strategy issues underlying mis...

Radiopharmaceuticals, Theranostics, and Nuclear Medicine

Small field dosimetry has been challenging without reasonable data. However, we've reached the point that the Monte Carlo approach can play a primary role in providing comprehensive beam data (including field output factors(FOFs), %dd and dose profiles, etc.)...