Loyola University Chicago

Therapy Physics

To auto-classify radiation oncology safety events reported in narrative descriptions using a large language model (LLM) and propose a framework for future AI-assisted reporting systems.

Markerless tumor tracking (MTT) using single-energy (SE) kilovoltage (kV) imaging is being considered for lung tumor motion management. However, bone overlap with tumor can reduce visibility and tracking accuracy. Dual-energy (DE) imaging suppresses bone and...

Deep learning models have shown promise for image-quality rating tasks, yet the visual cues they rely on are often difficult to interpret. Grad-CAM and related saliency methods are commonly used to visualize attribution, but these heatmaps often yield unclear...

To assess the effect of virtual monoenergetic image (VMI) energy variation (50-160 keV) on the accuracy of auto-generated contours using commercial autocontouring software.

To quantitatively and qualitatively assess CBCT image quality and achievable dose optimization following an upgrade from an aSi1200 to HyperSight imaging panel.

Inorganic scintillating detectors offer high-precision and high spatiotemporal resolution dosimetry for small-field radiotherapy applications such as SRS, SBRT, and SFRT. This study examines the impact of detector materials and volume on dose distributions to...

Eclipse v18 introduces an enhanced leaf model (ELM) for multileaf collimator (MLC) configuration. The model requires dosimetric measurements acquired with MLC-shaped fields and is therefore sensitive to leaf condition. Although leaf cleaning is commonly recom...

Deformable image registration (DIR) is integral to imaging alignment in radiation therapy, yet quality assurance (QA) on DIR performance remains challenging when reference contours are unavailable. In such situations, clinical decisions on acceptance of DIR r...

To characterize the three-dimensional (3D) isocenter behavior of the Halcyon linear accelerator as a function of off-axis distance and multileaf collimator (MLC) layer, and to evaluate the need for spatially resolved isocenter metrics beyond a single-value sp...

HyperSight CBCT (hCBCT) on Halcyon 4.0 provides image quality comparable to planning CT (pCT), supporting development of an offline adaptive radiotherapy (OART) workflow. This study evaluated the clinical feasibility of implementing an hCBCT-based OART workfl...

Osteoarthritis (OA) affects nearly one in four adults worldwide and has become an escalating public health concern. Medical and surgical interventions often carry notable morbidity, cost, and side effects. As a noninvasive alternative, low-dose radiotherapy (...

To develop a predictive tool to assess need for treatment plan adaptation.