Institute of Modern Physics

For proton spots to be deliverable, the intensity of each spot must either be zero or exceed a specific minimum monitor unit (MMU) threshold, which is a nonconvex problem. This study develops a quantum computing (QC)-based optimization framework to address th...

Lattice radiotherapy (LRT) is a spatially fractionated radiation technique that creates three-dimensional arrays of high-dose vertices within tumor volumes. Current LRT implementations face geometric constraints in small and medium-sized tumors, primarily due...

Proton minibeam radiation therapy (pMBRT) reduces normal tissue toxicity while preserving tumor control through spatial dose fractionation. However, multi-slit collimators (MSCs) substantially increase monitor unit requirements and delivery times, limiting cl...