Dana Farber Cancer Institute

Conventional radiotherapy dose (Gy) quantifies deposited energy, but response is influenced by the local radiochemical environment driving indirect DNA damage. Superoxide is a comparatively long-lived paramagnetic radical species showing potential as a marker...

To characterize the microsecond-scale dynamics of the free induction decay (FID) of a 0.35T Magnetic Resonance (MR)-guided Linear Accelerator (MR-Linac) during irradiation.

Phase II and III clinical trials establish standards of care in radiation oncology; however, achieving equivalent clinical outcomes in routine practice depends on the reproducible implementation of trial protocols. We systematically evaluated whether publishe...

In radiation oncology, phase I clinical trials often test the new capabilities of a treatment machine, a novel radiopharmaceutical drug, or an untested clinical indication of radiation therapy. These trials require significant physics investment of time and e...

Biologically‑guided Adaptive Radiotherapy (BIGART) on clinical MR‑linac systems are increasingly enabled by quantitative MRI that can sense early biology, beyond conventional anatomy. This symposium spotlights innovation in quantitative MRI and their potentia...

Ultrasound (US)-guided breast biopsy is widely used due to its accessibility and real-time visualization, but operator dependence can contribute to high false-negative sampling. Magnetic resonance imaging (MRI)-guided biopsy offers high sensitivity but is com...