University Hospitals Seidman Cancer Center

To evaluate the impact of patient size on cone-beam CT (CBCT) image quality using iterative reconstruction approaches on the Varian Ethos HyperSight imaging system and to assess the adequacy of attenuation and scatter correction across patient sizes.

Therapy Physics

To develop a robust, institution-independent quality assurance model using heterogeneous datasets. By prioritizing generalizability over site-specific tuning, this model aims to predict and assist in the delineation of PTV contours for glioblastoma (GBM) usin...

Direct-to-unit (DTU) adaptive radiation therapy (ART) is an emerging workflow that reduces treatment delays for urgent radiation therapy by eliminating the need for a separate simulation scan. Despite increasing clinical adoption, standardized commissioning g...

Collimator orientation in single-isocenter multi-target (SIMT) SRS significantly impacts multileaf collimator (MLC) modulation and overall plan quality. We developed a machine learning (ML) framework to identify optimal collimator angles prior to Treatment Pl...

The purpose of this study was to characterize the dosimetric consequences of direct CBCT dose calculation for abdominal stereotactic adaptive radiotherapy by comparing dose distributions calculated on simulation CT (simCT) versus HyperSight CBCT (HsCBCT). Emp...

This study evaluates whether selective distance-based cropping of organs at risk (OARs) can improve target coverage and plan robustness for abdominal stereotactic adaptive radiation therapy using the Ethos 2.0 planning system. By reducing OAR volume and thus...

SRS MapCheck has been widely used for SRS pretreatment patient-specific quality assurance (PSQA); however, it requires multiple machine deliveries due to limited array size. To improve the pretreatment PSQA efficiency for Single Isocenter Multiple Target (SIM...

Functional connectivity (FC) derived from functional magnetic resonance imaging (fMRI) is a key marker of brain health and cognitive function. Most analyses rely on the blood-oxygen-level-dependent (BOLD) signal; however, BOLD reflects both neural activity an...

This work demonstrates the use of a weighted expected Dice similarity coefficient (wDSC) for optimizing isocenter placement in single-isocenter multi-target (SIMT) LINAC-based stereotactic radiosurgery (SRS).

Phase II and III clinical trials establish standards of care in radiation oncology; however, achieving equivalent clinical outcomes in routine practice depends on the reproducible implementation of trial protocols. We systematically evaluated whether publishe...

Inequitable access to advanced radiotherapy technologies creates gaps in residency education and limits training experiences. The AAPM Penn–Ohio–West Virginia (POWV) Chapter developed a structured Inter-Residency Exchange Program (IREP) to expand resident exp...

Therapy Physics

Therapy Physics

Clinical Trials Specialty Program