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Fred Hutchinson Cancer Center

Rank #109 · 9 unique linked submissions.

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Poster Poster Program
Uncertainty-Aware Multimodal Biomarker-Guided Treatment Response Prediction: Integrating FDG PET, T-cell Repertoire, and Inflammatory Cytokines with Conformal Uncertainty Quantification

Uncertainty-aware multimodal biomarker-guided treatment response prediction in metastatic NSCLC remains a critical unmet need to support robust therapy selection and adaptation over time. We developed a multimodal framework integrating FDG-PET, T-cell recepto...

Daniel S. Hippe
Therapy Physics
Poster Poster Program
A Cgan-Based Spatially-Resolved Prediction of Lung Tumor Response to Chemoradiation

Lung cancer is a leading global malignancy with high mortality. Radiotherapy is a critical treatment; however, current planning often suffers from subjective dose settings and side effects. This study aims to use a Conditional Generative Adversarial Network (...

Daniel S. Hippe
Radiopharmaceuticals, Theranostics, and Nuclear Medicine
Poster Poster Program
A Practical Framework for Safe Linac Coordinate System Standardization

Linear accelerator (LINAC) coordinate system conventions have historically evolved heterogeneously, with vendors and institutions adopting mixed non-IEC standards. While clinically functional, this lack of uniformity introduces added complexity and potential...

Myra Lavilla
Professional
Poster Poster Program
Uncertainty-Aware Multiscale Patient- and Voxel-Level Treatment Response Forecasting for Personalized Radiotherapy Using Conformal Prediction In Advanced Non-Small Cell Lung Cancer (NSCLC)

Multiscale treatment response prediction in advanced NSCLC enables spatially informed dose painting, yet prediction point estimates alone do not convey the uncertainty required for adaptive therapy decision support. We developed a multiscale conformal predict...

Daniel S. Hippe
Therapy Physics
Poster Poster Program
BLUE RIBBON POSTER RADIOPHARMACEUTICALS: Attention Med3D: A 3D Deep Learning Model Based on Transfer Learning and Attention Mechanism for Predicting Mid-Treatment Chemoradiation Response on FDG PET of La-NSCLC

Accurate assessment of early radiotherapy response in tumors provides crucial guidance for optimizing radiotherapy protocols. We developed a 3D deep learning model termed Attention Med3D based on transfer learning and attention mechanisms for predicting mid-t...

Daniel S. Hippe
Radiopharmaceuticals, Theranostics, and Nuclear Medicine
Paper Proffered Program
Clustering Model Based on 3DUNET-Gmm Combining 3D-Unet Feature Extracting with Gmm Clustering to Divide Tumor Subregions on FDG PET for La-NSCLC

Accurate identification of high-risk and low-risk tumor subregions enables radiographers to customize radiation dose distributions for biologically adaptive therapies. This study proposes a 3DUNET-GMM model that integrates 3D-UNet feature extracting with Gaus...

Daniel S. Hippe
Radiopharmaceuticals, Theranostics, and Nuclear Medicine