Wayne State University

To quantify uncertainty in SPECT sensitivity factor used for Lu-177 radiopharmaceutical dosimetry.

Coronary artery (CA) calcifications (CACs) connect upstream cardiovascular risks with downstream radiotherapy planning decisions, yet these powerful imaging biomarkers are underutilized in radiation oncology. We developed and validated an opportunistic screen...

To evaluate whether a low-density HU-override strategy can reduce Acuros XB (AXB) optimizer over-compensation when air volumes overlap the planning target volume (PTV), while maintaining dose coverage and robustness at the air–tissue interface and reducing ho...

To evaluate a novel dual-mode handheld gamma camera (RAVIN, M3D Inc.) utilizing coded aperture and Compton imaging for clinical radiopharmaceutical applications.

Tin filtration has shown improved dose efficiencies in conventional CT for renal stone imaging. Photon-counting CT (PCCT) enables virtual monoenergetic image (VMI) reconstructions that can enhance stone conspicuity. This study evaluates potential dose-efficie...

To evaluate a novel dual-mode handheld gamma camera (RAVIN, M3D Inc.) utilizing coded aperture and Compton imaging for clinical radiopharmaceutical applications.

To demonstrate a novel "Split-Brain" Multi-Agent Large Language Model framework for autonomous inverse planning in radiation oncology.

Cardiotoxicity is a devastating complication of cancer treatment. Notably, the heart is complex and dose to cardiac substructures (CS) have been strongly linked to radiation-induced cardiac morbidity. The physicist-led, NIH-funded “THE cARdiac Radiation Thera...

AI-based medical image segmentation has achieved strong performance across diverse tasks, yet progress remains constrained by ground truth availability. Interventional fluoroscopic angiography, a 2D modality with complex vascular anatomy, is underrepresented...

Accurate organ-at-risk segmentation remains a critical bottleneck in MR-guided adaptive radiotherapy, consuming 20–40 minutes per fraction. Current methods treat each fraction independently, discarding patient-specific information from prior sessions. We deve...

Adaptive radiation therapy (ART) for proton therapy relies on routine offline CT simulations for updated anatomy. To facilitate online proton ART, we present our high‑fidelity regularized Brownian Bridge (rBBrg) framework to perform deterministic cross-modali...

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