Diffuse midline glioma (DMG) is an aggressive central nervous system malignancy typically affecting children and requiring urgent radiotherapy treatment. This study evaluates the application of knowledge-based planning to expedite treatment planning and treat...
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University of Sydney
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To investigate the feasibility and potential benefits of biologically optimised treatment planning (BiRT) utilizing heterogeneous focal-boost prescriptions based on patient-specific cell density distributions. This study compares conventional high-dose-rate b...
MLC backlash is a linac failure mode that results in MLC positional error that has been demonstrated to not be prevented by the linac’s internal safety systems [1]. This study aims to inform on the clinical significance of MLC positional error due to MLC back...
Radiotherapy quality assurance (RTQA) of target volume delineation is critical in clinical trials to ensure protocol adherence. Manual real-time review is resource-intensive and often limited to a subset of patients. This study evaluates the feasibility of au...
During liver radiotherapy, respiratory-induced tumor motion can result in target underdose and increased irradiation of surrounding healthy tissue. Existing real-time image-guided approaches often require specialized equipment or invasive marker implantation...
In interventional radiology, the precise 3D localization of mobile targets, particularly within the thorax, is of utmost importance. While conventional modalities such as Cone Beam CT (CBCT) provide necessary depth information, they are unsuitable for real-ti...
Targeting accuracy in stereotactic ablative body radiotherapy (SABR) for hepatocellular carcinoma (HCC) is often hindered by the poor soft-tissue visibility of tumors on standard image-guided radiotherapy using kilovoltage (kV) images. However, ~60% of HCC pa...
Clinical practice in radiotherapy medical physics is strengthened through shared experience and peer learning. Although peer-reviewed outputs and educational resources are essential, they are often insufficiently timely, specific, or practical for day-to-day...