To demonstrate a novel method of quantifying respiratory gating beam-on and beam-off latency for Varian TrueBeam linear accelerators and assess the impact of dose rate and machine-specific factors on overall timing performance.
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London Health Sciences Centre
Rank #96 · 10 unique linked submissions.
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In head-and-neck radiotherapy, relatively large planning target volume (PTV) margins of 5-mm are standardly used to account for setup uncertainty and anatomical variations. However, this comes at the expense of increased dose to nearby structures, resulting i...
Radiotherapy planning for liver tumours remains challenging due to low tumour conspicuity and respiratory motion. This study explores the conditions under which dynamic contrast enhanced (DCE)-CT can be used to enhance tumour delineation for radiotherapy plan...
Stereotactic body radiotherapy (SBRT) plays a central role in the management of early-stage and oligometastatic lung cancer. Over recent years, there has been significant interest in automating treatment planning through the development of knowledge-based pla...
To demonstrate feasibility of three-dimensional ultrasound (3DUS) for the detection of oral squamous cell carcinoma (OSCC) and to evaluate its potential as a pre-clinical screening tool.
To develop and evaluate a custom convolutional neural network (CNN) using baseline 68Ga-DOTATATE PET/CT imaging to predict disease control following 177Lu-DOTATATE therapy in patients with neuroendocrine tumors (NETs).
Cardiac radioablation is one of the most demanding applications in radiation oncology, requiring high-dose conformity and steep dose gradients. Conventional C-arm systems, such as Varian TrueBeam (Varian – a Siemens Healthineers Company, Palo Alto, CA), relia...
Accurately identifying clinically significant prostate cancer (PCa) lesions remains a difficult task. Although tumor characteristics associated with false-negative lesions have been investigated, the potential radiologist search strategy issues underlying mis...
We previously developed a system capable of acquiring accurate transrectal 3D micro-ultrasound (mUS) images to allow for visualization and focal treatment of intra-prostatic lesions during prostate brachytherapy. This system made use of a mUS probe with non-s...
Two key challenges in pharmacokinetic modeling (PKM) of dynamic PET are metabolite contamination of the image-derived arterial input function (AIF) and the presence of these metabolites in tissue time-activity curves (TACs). We propose a method to correct for...