Indiana University School of Medicine

Shortages of trained medical physicists persist across Africa. Needs-assessment surveys were utilized to determine trainee interest and medical physics curricular gaps to aid in design of hands-on outreach workshops for the African School of Physics, a severa...

To commission and clinically implement a modified Stanford technique for Total Skin Electron Irradiation (TSEI) using a standard TrueBeam linac, achieving consistent and high-quality skin dose coverage.

To evaluate dosimetric characteristics and biological dose delivered via abbreviated regimen combining single-fraction HDR brachytherapy (15 Gy) with ultra-hypofractionated elective pelvic radiation therapy (ePUHRT, 25 Gy in 5 fractions) for unfavorable inter...

Standard dose optimization fails in low-resource settings due to unique patient phenotypes, heterogeneous aging equipment, and absent validation pathways. This work presents a closed-loop digital twin ecosystem that autonomously synthesizes institution-specif...

Access to radiation therapy remains a major challenge in many low‑ and middle‑income countries (LMICs), where limited infrastructure and workforce shortages hinder timely cancer treatment. Moi Teaching and Referral Hospital (MTRH) in Eldoret, Kenya, is an Aca...

Hypertensive heart disease in Africa progresses as a silent epidemic of myocardial fibrosis, undetectable by conventional echocardiography until irreversible failure. This study hypothesized that early fibrosis manifests as a perturbation in ultrasonic scatte...

Convolution/superposition is a widely-used method for radiotherapy dose calculation, in which energy deposited at the first interaction point (TERMA) is convolved with a scatter kernel to obtain the dose. To account for tissue heterogeneities, the kernel can...

This study investigates the hematological consequences of chronic low-dose radiation exposure (0.1–20 mSv/year) among radiology professionals, assessing profession-specific vulnerabilities and identifying biomarkers for early biological impact below regulator...

Noninvasive stereotactic radioablation for refractory ventricular tachycardia (rVT) using a single 25 Gy fraction is an emerging treatment option for patients with advanced heart failure. This complex procedure requires highly non-coplanar beam geometry, stri...

This study models clinical outcomes of SFRT treatments delivered using the 3D MLC-based Crossfire technique.

We present the results of anthropomorphic phantoms (IROC Houston) irradiations at 2-academic institutions for independent verification of highly heterogenous dose distributions via 3D MLC-based SFRT plans for credentialling multi-institutional site-specific c...

Accurate segmentation of the left anterior descending (LAD) coronary artery is essential for cardiac sparing in thoracic radiotherapy, particularly for lung cancer patients receiving high-dose radiation near the heart. However, the LAD is thin, low-contrast,...

We investigated optimal geometric parameters for spatially fractionated radiotherapy (SFRT) through in-vitro experiments.

External beam radiotherapy (RT) for ocular tumors is challenged by intra-fractional ocular motion. Although thermoplastic immobilization masks reduce head mobility, eye mobility remains problematic. Current motion-management options, including COMS brachyther...