Institution profile
Rank #186 · 5 unique linked submissions.
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The overarching goal is to develop a novel system for microdosimetry integrated with cellular molecular radiation response using Monte Carlo (MC) simulations, Raman spectroscopy (RS), and radiobiological assays. MC simulations of the system and initial invest...
To apply label-free multimodal nonlinear optical (NLO) imaging including stimulated Raman scattering (SRS) and two-photon excitation fluorescence (TPEF) microscopy for multiplex single-shot identification of metabolic biomarkers of radiobiological response to...
To determine whether a supervised machine learning (SML) approach to low-dose biodosimetry, trained on radiation-induced chromosomal translocations of astronauts and individual radiation response covariates, could be an alternative method for dose estimation.
Biodosimetry (BD) correlates biological damage from radiation exposure to absorbed dose, providing an accurate method of dose assessment that accounts for individual biological factors. The goal of this project is to modify an existing lymphocyte BD methodolo...
To develop a Raman spectroscopy (RS)-based experimental microdosimetry system capable of read-out of a model system of cells cultured on a radiochromic film (RCF) dosimeter substrate that can measure energy deposited by ionizing radiation within individual ce...