Arthur J.E. Child Comprehensive Cancer Centre

To quantify the geometric accuracy of an automatic applicator anchor point placement framework for cervical cancer (CC) high-dose-rate (HDR) brachytherapy implemented in Oncentra Brachy (Elekta).

HyperArc is an automated planning and delivery technique for single and multiple-target stereotactic radiosurgery (SRS) treatments that creates highly conformal plans and has potential for saving time. This study evaluates whether HyperArc SRS plans have a no...

To optimize a curve-fitting model for quantitative T1-mapping via inversion recovery (IR) sequences considering varying numbers of data points. For clinical applications, higher resolution and shorter scan times are desired.

Open-faced thermoplastic masks are widely used for immobilization in stereotactic radiosurgery (SRS) to achieve submillimeter treatment accuracy. This study compared the performance of two commercially available mask designs for SRS patients: the dual-layer O...

Winston-Lutz (WL) testing is routinely used to assess coincidence between a linac’s mechanical and radiation isocenter. Although dedicated commercial phantoms exist for off-axis target verification, they require additional resources and training. The QUASARTM...

Geometric distortions in MRI increase with distance from the magnetic isocenter and may impact spatial accuracy in gynecological interstitial brachytherapy (ISBT). This is particularly relevant for ISBT techniques, such as the Syed-Neblett template, where nee...

Craniospinal irradiation (CSI) can be delivered using a multi-isocentre technique. This requires a time-consuming alignment process using kV orthogonal imaging followed by cone-beam CT (CBCT) to ensure alignment accuracy across multiple anatomical regions. Su...

Weisskoff analysis assesses temporal stability of echo-planar imaging (EPI) in functional MRI (fMRI) by comparing how the temporal coefficient of variation (CoV) scales with ROI size relative to uncorrelated noise (e.g. ideal scaling) to assess unwanted inter...

To improve lung-sparing for multi-isocentric total body irradiation (TBI) in adult-sized patients while preserving target coverage, and to determine mean lung dose (MLD) and target maximum dose (PTV D1cc) as a function of body dimensions.

To optimize diffusion-kurtosis imaging (DKI) MRI acquisitions for improved time efficiency while preserving quantitative data fidelity, enabling the future integration of DKI into cancer-care workflows for RT treatment planning and disease tracking.

To evaluate the relationship between quantitative MRI relaxation parameters (T1, T2, T*2, and T'2) at 3T and hypoxia level in three-dimensional (3D) cancer cell spheroids under controlled in-vitro conditions, using western blot measurements as biological grou...

To optimize a Fricke xylenol orange (FXO) gel formulation for high-sensitivity readout using optical computed tomography (optical CT) and magnetic resonance imaging (MRI), and to quantitatively demonstrate that MRI-based readout provides three-dimensional (3D...

While transrectal ultrasound (TRUS) is the primary modality for guidance and planning in high-dose-rate prostate brachytherapy (HDR-BT), magnetic resonance imaging (MRI) is required for identifying and targeting the dominant intraprostatic lesion (DIL). The p...

Recent discontinuation of OSLDs prompted the adoption of MOSFETs as an alternative for in-vivo dose verification for patients with cardiac implantable electronic devices (CIEDs). We characterized MOSFET response across clinically relevant beam delivery parame...

This work describes the development of a flexible educational framework designed to address required curriculum and professional competencies for Radiation Oncology (RO) and Medical Physics (MP) residents implemented in two distinct clinical and academic envi...

Clinical innovation is essential for advancing radiation therapy and is often led by clinically medical physicists. As the clinical and academic landscape evolves, establishing a research portfolio presents challenges and new opportunities for medical physici...

To quantify the dosimetric impact of transitioning from water-based TG-43 dose evaluations to advanced model-based TG-186 calculations in permanent prostate brachytherapy, and to assess the effects on target coverage, organ-at-risk doses, and the appropriaten...

Diagnostic and Interventional Radiology Physics