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German Cancer Research Center (DKFZ)

Rank #231 · 4 unique linked submissions.

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Poster Poster Program
Development and Advanced Characterization of an X-Ray Flash Benchtop

Ultra-high dose rate (FLASH) irradiation has demonstrated the potential to spare normal tissue while maintaining tumor control, yet its underlying mechanisms remain unclear, particularly for low-energy X-rays where radiation quality and linear energy transfer...

Joao Seco, PhD
Therapy Physics
Paper Proffered Program
Radiation Particle Type and Tumor Immune Microenvironment Modulate KRAS Inhibitor-Radiotherapy Synergy and Overcome KRAS Inhibitor Resistance In Pancreatic Cancer

Enhanced relative biological effectiveness (RBE) Carbon Ion Radiotherapy (CIRT) may provide a promising tool to eradicate therapy-resistant tumors such as pancreatic ductal adenocarcinoma (PDAC). Novel KRASG12D inhibitors have demonstrated CD8+ T-cell depende...

Mahdi Akbarpour, DVM, MSc, PhDMahmoud Moustafa, PhDSaleh Eskandarian, MS
Therapy Physics