Ultra-high dose rate (FLASH) irradiation has demonstrated the potential to spare normal tissue while maintaining tumor control, yet its underlying mechanisms remain unclear, particularly for low-energy X-rays where radiation quality and linear energy transfer...
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German Cancer Research Center (DKFZ)
Rank #231 · 4 unique linked submissions.
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The purpose of this study was to implement and experimentally characterize a kV microbeam X-ray irradiation platform, with emphasis on spatial dose modulation and dosimetric suitability for future radiobiological applications. Spatially Fractionated Radiation...
A novel in vivo method to monitor bone cancer during particle therapy that uses prompt gamma-ray spectroscopy (PGS) to quantify bone density and calcium (Ca) content. Upon bone irradiation with a particle beam, Ca-specific gamma emissions are induced by inela...
Enhanced relative biological effectiveness (RBE) Carbon Ion Radiotherapy (CIRT) may provide a promising tool to eradicate therapy-resistant tumors such as pancreatic ductal adenocarcinoma (PDAC). Novel KRASG12D inhibitors have demonstrated CD8+ T-cell depende...