Université Laval

In current prostate permanent implant (PPI) low-dose-rate (LDR) brachytherapy planning, algorithm-generated treatment plans are frequently sub-optimal, requiring time-consuming and user-dependent manual adjustments. This work aims to develop and evaluate a GP...

Two-dimensional dosimetry for radiotherapy quality assurance commonly relies on planar detector arrays or radiochromic film. While these methods provide high spatial resolution, they are often time-consuming, single-use, and do not provide real-time feedback....

Measuring dose from small fields delivered by dedicated radiosurgery devices like the Gamma Knife can be challenging and time consuming. It usually required a combination of films and point detectors (diodes, micro-ion chamber). Our goal is to facilitate radi...

Plastic Scintillation Detectors (PSD) have shown great potential for dose measurements, but extraction of dwell-time in particular sub-seconds is plagued with small signal. This study aims to evaluate inorganic scintillator (ISD) performances in terms of Sign...

HDR prostate brachytherapy (HDR-PBT) treatment plans are subject to multiple uncertainties that can significantly impact delivered dose distributions. This work implements a comprehensive robust evaluation framework in the context of multi-criteria optimizati...

Preclinical studies with small animals require precise control to yield conclusive results. Small animal irradiations differ from clinical irradiations and can push dose calculation algorithm to their limits: small volumes, small fields, superficial treatment...

With the recent introduction of clinical MR-Linac devices, there is an increased need for dose measurement techniques unaffected by magnetic fields. Polarized Cherenkov imaging is a luminescence-based dosimetry method potentially well suited for MR-Linac meas...

To quantify recovery of damaged plastic scintillators and optical fiber after exposure to ultra-high dose rate (UHDR) protons, in terms of light output and spectral signature.

An important component of the patient positioning and monitoring in Gamma Knife treatments, is the integrated CBCT system. However, the current circular arc scan trajectory and the geometric constraints on the CBCT system imposed by the machine, causes notice...

Experimentally extract and validate the correction factors, including ionization quenching, to be applied to dose rates measured with a Plastic Scintillation Detector (PSD) for In-Vivo Dosimetry (IVD) in High Dose Rate (HDR) brachytherapy.

To develop an optical detector for daily quality assurance (QA) of the 80 multileaf collimator (MLC) leaf pairs of an Elekta Unity MR-LINAC.

To quantify the dosimetric impact of transitioning from water-based TG-43 dose evaluations to advanced model-based TG-186 calculations in permanent prostate brachytherapy, and to assess the effects on target coverage, organ-at-risk doses, and the appropriaten...

Novel GPU-based multicriteria optimization (gMCO) for high-dose-rate gynecological brachytherapy (GYN-BT) generates large plan pools satisfying EMBRACE-II dosimetric constraints (Pötter et al., 2018). Differentiating plans with comparable dosimetry but potent...

FLASH radiotherapy, defined by ultra-high dose rates (UHDR; >40 Gy/s), can reduce normal-tissue toxicity while maintaining tumor control, yet reported FLASH effects show substantial variability across experimental and preclinical studies. Dielectric materials...

Apparent diffusion coefficient (ADC) is a widely used marker of tumor cellularity in diffusion MRI, but ADC values depend on b-value selection and are prone to reduced tumor conspicuity in the presence of edema. Restriction Spectrum Imaging (RSI) leverages mu...

Therapy Physics

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