Shanghai Jiao Tong University

FLASH radiation therapy, which utilizes FLASH effect with ultra-high-dose-rate (UHDR) radiation, has shown promising performance in achieving treatment goals with decreased risks on healthy organs of patients. However, a number of factors, including patient-s...

Conventional intensity-modulated proton therapy (IMPT) planning commonly relies on fixed, uniformly distributed spot grids with optimization restricted to spot weights. Although adaptive spot placement has been explored to improve dose conformity, particularl...