Southern Medical University

To develop a quantitative plan quality scoring (PQS) tool for evaluation of left-sided breast radiotherapy plans and to compare performance across four platforms.

To prospectively validate a prior and constraint-informed deep learning auto-segmentation framework for nasopharyngeal carcinoma (NPC) across three clinical centers, addressing accuracy, efficiency, and anatomical plausibility under real-world time constraint...

In lung cancer adaptive radiation therapy (ART), respiratory motion and interfractional anatomical variations—including changes in tumor size and normal tissue anatomy—can affect the efficacy of radiation treatment. Acquiring high-quality 4D-CBCT (cone beam c...

In the microdosimetric kinetic model (MKM), the quadratic coefficient β is commonly assumed to be independent of linear energy transfer (LET). However, experimental data suggest that β decreases at very high LET, likely because the conventional MKM does not e...

Volumetric modulated arc therapy (VMAT) planning is complex and time-consuming. This study proposes a direct VMAT plan generation method for cervical cancer, enhanced by a physics-guided 3D dose-domain supervision strategy to ensure dosimetric quality.

Although consolidative immunotherapy following radiotherapy is standard for locally advanced non-small cell lung cancer (NSCLC), this combination increases the risk of ≥ Grade 2 symptomatic pneumonia (SP). This study utilized an explainable deep learning (DL)...

To develop a multi-omics data integration method based on ensemble learning to construct a prognostic decision model for MRI-guided radiotherapy in gliomas, providing reliable reference for clinical decision-making.

X-ray-induced acoustic (XA) imaging provides a potential solution for noninvasive, real-time 3D dose verification by characterizing the radiation-induced thermoelastic effect. However, clinical implementation is severely hampered by limited-view sampling and...

Lattice radiation therapy (LRT) is an innovative radiotherapy technique lacking the standardized approach for the spatial distribution of high-dose regions. Manual placement is time-consuming and subjective. Automated regular geometric lattice arrangements ca...