Keck School of Medicine of USC

This study explored the clinical feasibility of implementing simultaneous integrated boost (SIB) GRID therapy planning technique for Spatially Fractionated Radiotherapy (SFRT).

Spatially Fractionated Radiation therapy (SFRT) and brachytherapy both have high dose heterogeneity featuring localized high-dose regions and steep dose gradients. While SFRT techniques such as GRID and Lattice intentionally create heterogeneous dose distribu...

Spatially fractionated radiation therapy (SFRT) aims to deliver high-dose peaks within tumors while maintaining low-dose valleys. However, commonly used peak-to-valley ratios or D5/D95 and D10/D90 metrics derived from gross tumor volume (GTV) DVHs fail to acc...

The Varian Halcyon linear accelerator, featuring a ring-gantry design and dual-layer multileaf collimator (MLC), has gained increasing clinical adoption due to its streamlined workflow and operational efficiency. Unlike conventional C-arm linacs, Halcyon comm...

Monthly TG-142 dosimetry quality assurance (QA) remains labor-intensive, creating workflow burden in high-throughput clinical environments. Although ion chamber arrays are widely available, their use for comprehensive TG-142 monthly dosimetry QA has not been...

Spatially Fractionated Radiation Therapy (SFRT) has generated significant interest as a promising approach for treating bulky and resistant tumors. Its effectiveness stems not only from the underlying physics and dosimetry but also from advances in modern rad...