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University of Rhode Island

Rank #400 · 2 unique linked submissions.

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Poster Poster Program
Enhanced Phlip (e-pHLIP) for Targeted Cytoplasmic Delivery of Polar Payloads

pH Low Insertion Peptide (pHLIP) technology is employed in clinics for targeting of tumors and delivery of imaging and therapeutic agents. Here we introduced the novel enhanced pHLIP (e-pHLIP) system for efficient cytoplasmic delivery of large polar payloads,...

Yana Reshetnyak, PhDMarissa Iraca, MScAnna Moshnikova, PhDCraig Klumpp, MScOleg Andreev, PhD
Radiopharmaceuticals, Theranostics, and Nuclear Medicine
Poster Poster Program
Novel Generation of PHLIP Peptides for Targeted Delivery of Imaging and Therapeutic Payloads to Tumors

pHLIP (pH (Low) Insertion Peptides) technology is used in preclinical and clinical studies for targeted delivery of imaging and therapeutic agents to acidic tumors. pHLIPs sense low pH at the surface of cancer and immune cells, insert into cellular membrane a...

Craig Klumpp, MScMarissa Iraca, MScJohn BelangerYana Reshetnyak, PhDOleg Andreev, PhDAnna Moshnikova, PhD
Therapy Physics