Michigan State University

To investigate whether the apparent diffusion coefficient (ADC) from diffusion-weighted imaging (DWI) acquired at a 0.35T MR-Linac can determine prostate and intraprostatic lesion changes caused by adaptive radiotherapy performed on this treatment modality.

We compared denoising methods for Diffusion-Weighted Imaging (DWI) of phantoms acquired on a low-field MR-Linac to determine which method best preserves Apparent Diffusion Coefficient (ADC) accuracy and image feature detection. Our goal was to quantify image...

Dynamic contrast-enhanced (DCE)-MRI is widely used to assess vascular perfusion and permeability; however, conventional time-domain pharmacokinetic models often conflate flow- and leakage-driven transport. This study introduces a Laplace-domain framework to q...

Automated stereotactic radiosurgery (SRS) planning often fails to match the high conformity and complex trade-off logic of expert human dosimetrists. We hypothesized that a reasoning-based AI agent, SAGE (Secure Agent for Generative dose Expertise), could gen...