Ultra-high dose rate (UHDR) beams (40Gy/s) compromise the accuracy of conventional reference ion chambers (ICs) due to saturation effects. The Exradin A30 is an ultra-thin parallel-plate IC featuring a 0.3 mm nominal electrode spacing to enhance the charge co...
Author profile
Ahtesham Ullah Khan, PhD, MS
Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison
We present advancements of single-molecule biodosimetry to measure radiation-induced DNA damage from α-emitting 225Ac. These results will be compared to β-emitting radionuclides to assess relative biological effectiveness (RBE) for radionuclide therapies.
To experimentally determine the effective point of measurement (EPOM) shift of an Exradin A1SL ion chamber in kilovoltage x-ray beams (40-250 kVp) using water tank measurements.
To evaluate the accuracy of high-resolution radiochromic film dosimetry for characterizing peak and valley dose distributions in microbeam radiation therapy (MRT). This study aims to establish film as a benchmark for validating the spatial and dosimetric accu...
To investigate whether ultra-high dose rate (UHDR) electron beams induce a FLASH effect, quantified through differential gene expression in the plant species Arabidopsis thaliana.
Development of next-generation neutron capture therapy (NCT) agents demands rigorous preclinical testing to verify targeting efficacy, safety, and therapeutic gain under clinically relevant irradiation conditions. This work proposes a preclinical, accelerator...
The Liberty Vision Y-90 ophthalmic applicator (LV-90) is an FDA approved HDR source for episcleral brachytherapy to treat ocular tumors and benign growths. It is an attractive option for patients because it does not require episcleral sutures, muscle relocati...
Accurate absorbed dose determination for alpha emitting sources remains challenging due to short particle ranges and sensitivity to source geometry. This work presents a practical framework for direct absorbed dose to water measurements from a plated 241Am so...