To evaluate the delivery accuracy and treatment plan quality of the RefleXion X2 system with a developmental anchor point tracking delivery algorithm for large PET-avid targets, with specific emphasis on the treatment planning and performance improvements.
Author profile
Timothy Pok Chi Yeung, PhD
RefleXion Medical
Gravity exerts a force on the X1 causing gantry flexion, albeit small, that can be minimized to improve targeting accuracy while it is rotating. This study sought to demonstrate the mitigation of gravity-induced effects by improving the centering of the jaws...
This work demonstrates the dosimetric performance of the developmental Anchor Point Tracking algorithm using phantom data acquired on the RefleXion X2 system with wide field-of-view PET detectors and software emulation of treatment planning and delivery.
The RefleXion X1 system requires activity concentration (AC) >5 kBq/mL for successful biology-guided radiotherapy (BgRT). We evaluated whether the extended field-of-view (FOV) PET detector in a can lower this AC threshold and expand treatment eligibility.
To assess the effectiveness of a developmental anchor point tracking algorithm with PET deblurring in targeting tumors on the RefleXion X2 platform.
To evaluate the robustness of the developmental X2 Anchor Point Tracking algorithm to changes in breathing patterns between SCINTIX-modeling PET (for planning) and biology-guided radiation therapy (BgRT) treatment.