Sagar Patel, MD

This study quantifies how two inverse optimization-based planning parameters: dwell time deviation constraint (DTDC) and active step size (AS) affect target coverage, dose heterogeneity, and organ‑at‑risk (OAR) doses in prostate high dose rate (HDR) brachythe...

Proton prostate SBRT is characterized by steep dose gradients and elevated linear energy transfer (LET) near the end of range, which may contribute to genitourinary (GU) toxicity. Prior work suggests that bladder neck (trigone) dose is a stronger predictor of...