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Author profile
Meng Wei Ho, MS
New York Proton Center
Clinical Implications of LET-to-Water Versus LET-to-Medium Calculations In Heterogeneous Head-and-Neck Proton Therapy Scenarios
Dose-averaged linear energy transfer (LETd) is increasingly used to characterize biological risk in proton therapy. However, LET definitions differ among treatment planning systems. RayStation 2023B reports LET-to-water, whereas Monte Carlo engines such as MC...
Poster Program · Therapy Physics
Free-Breathing–Gated Delivery Can Achieve High-Quality Proton Treatment for Lung Cancer Patients
While 30% of lung cancer patients cannot tolerate breath-hold, free-breathing(FB) proton pencil-beam-scanning(PBS) deliveries compromise target coverage from the interplay effects of large motion. This study presents a novel FB-gated spirometer-based respirat...
Poster Program · Therapy Physics
Risk Informed Workflow and Disease Specific Milestones Ensure Safe Patient Transfer and Treatment between Proton Therapy Centers
With the number of proton centers increasing, each facing intermittent downtime or need for renovations. Developing optimal approaches to maintain uninterrupted treatment is essential to preserve clinical outcomes. This study outlines key risk factors, workfl...
Poster Program · Therapy Physics
Dose-Gated, Letd-Triggered Signatures of Mandibular Osteoradionecrosis (ORN) after Head-and-Neck Intensity Modulated Proton Therapy
Linear energy transfer (LETd) has been implicated in mandibular osteoradionecrosis (ORN) following proton therapy; however, its strong spatial coupling with dose has limited interpretation of whether LETd contributes independently to ORN risk. This study aims...
Proffered Program · Therapy Physics