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New York Proton Center
Traditional patient-specific QA in proton therapy requires detector-based measurements that consume beam time and delay workflow. This study presents a calibration-based machine log analysis system enabling automated, measurement-free verification of delivere...
Dose-averaged linear energy transfer (LETd) is increasingly used to characterize biological risk in proton therapy. However, LET definitions differ among treatment planning systems. RayStation 2023B reports LET-to-water, whereas Monte Carlo engines such as MC...
Dose–volume metrics alone incompletely explains mandibular osteoradionecrosis (ORN) following proton therapy. LET-based aggregate approaches such as dose–LET volume histograms (DLVH) implicitly assume uniform LET contribution across dose levels. This study in...
Linear energy transfer (LETd) has been implicated in mandibular osteoradionecrosis (ORN) following proton therapy; however, its strong spatial coupling with dose has limited interpretation of whether LETd contributes independently to ORN risk. This study aims...