wangyao li

Carbon ion radiotherapy (CIRT) offers high LET and RBE for treating radioresistant tumors but suffers from biological dose inhomogeneity due to RBE uncertainties. Techniques like LET painting focus on optimizing LET but do not directly address biological effe...

Proton LATTICE (pLATTICE) therapy delivers spatially heterogeneous dose distributions with high‑dose peaks embedded within low‑dose valleys. Conventional pLATTICE planning typically uses multiple beam angles per peak, making peak localization vulnerable to pr...