Author profile
The University of Texas MD Anderson Cancer Center
To apply a proton procedure of optimizing spot weight and Ridge Filter (RF) to single-energy carbon pencil beam and evaluate it in a water phantom with a square-shape target in the center (prescription dose 50 Gy).
To develop an optimization procedure of spot weight and ridge filter (RF) dimension for single-energy proton pencil beam and apply it to a water phantom with a square-shape target in the center (prescription dose 50 Gy).
Current clinical toxicity models for predicting radiation-induced pneumonitis are limited by lack of functional information; furthermore, current practice assumes a relative biological effectiveness (RBE) of 1.1 for proton therapy patients. We hypothesize tha...
Enhanced relative biological effectiveness (RBE) Carbon Ion Radiotherapy (CIRT) may provide a promising tool to eradicate therapy-resistant tumors such as pancreatic ductal adenocarcinoma (PDAC). Novel KRASG12D inhibitors have demonstrated CD8+ T-cell depende...
FLASH radiotherapy (FLASH‑RT) employs ultra‑high dose rates (UHDR) that preferentially spare normal tissues relative to conventional dose‑rate radiotherapy (CONV‑RT) while maintaining tumor control, this is known as the FLASH effect. A proposed mechanistic ex...
To design and validate a phantom capable of remote temporal and point dose rate assessment for electron and proton FLASH beams, with integrated spatial information to enable full end to end verification.
The sensitivity of normal liver tissue raises concerns about potential liver function post-cancer treatment. We investigate whether liver radiomics features derived from standard CT-guided radiation therapy (RT) can improve acute functional liver decline pred...