Gaolong Zhang, PhD

In proton therapy with pencil beam scanning (PBS), repainting mitigates respiratory motion effects but increases treatment time, burdening patients who must remain on the couch for extended periods. To address this challenge, we propose an advanced planning s...

Dose-mimicking aims to generate treatment plans based on a reference dose distribution. The importance of dose-mimicking has grown substantially due to the increasing demand for rapid plan adaptation in adaptive radiotherapy—particularly in proton therapy, wh...

Intensity-modulated proton therapy (IMPT) with pencil beam scanning (PBS) delivers sequential proton spots as the fundamental delivery unit. By tuning each spot’s spatial position, energy level, and fluence intensity, it enables layer-by-layer tumor target do...

CBCT is routinely acquired prior to proton therapy for patient setup. However, the limited image quality of CBCT compromises the dose calculation accuracy and limits its use for treatment plan adjustments. This study aims to develop a high-performance CBCT-to...

Monte Carlo (MC) simulation is the gold standard for dose calculation in radiation therapy, as it can accurately reproduce the interaction processes between photons and human tissues in intensity-modulated radiation therapy (IMRT) and generate high-precision...

During radiotherapy, anatomical changes may impact the suitability of the initial treatment plan, necessitating the application of adaptive radiation therapy (ART). The MVCT serves as the patient positioning image, enabling dose reconstruction. However, its l...

High-risk locally advanced cervical cancer (HR-LACC) remains challenging due to its heterogeneous prognosis and high recurrence rates, underscoring the need for precise and personalized treatment strategies. This study aims to develop and validate an interpre...