Author profile
Medical Physics Department, Princess Margaret Cancer Center, University Health Network
Cervical cancer remains a major global health burden, with Image-guided High-Dose-Rate Brachytherapy (HDR-BT) serving as a critical treatment modality. While MRI is the gold standard for defining the Gross Tumor Volume (GTV), High-Risk Clinical Target Volume...
This project uses a multi-modal method to train a foundational model for medical images of cervical cancer patients. Multiple imaging modalities are used over the course of treatment: multiparametric MRI, CT, cone-beam CT, and PET when indicated. This motivat...
High dose-rate brachytherapy (HDR-BT) is an essential component of cervical cancer treatment. While deep learning has shown promise to automate tasks within HDR-BT, such as segmentation of organs-at-risk (OARs) and targets, quality labelled data is limited. T...
18F-fluorodeoxygluose positron emission tomography (18F-FDG-PET) is clinically useful in cervical cancer care and has been shown to reduce interobserver variation of the residual gross tumour volume in brachytherapy. Chemical exchange saturation transfer MRI...
Peer review is a critical quality assurance step in radiation therapy (RT), but not all cases require the same level of attention. We aimed to develop a machine learning (ML) tool to help prioritize breast RT plans for peer review based on their likelihood of...
Small variations in radiochromic material thickness in films leads to variability in sensitivity and uncertainty in measured dose. To achieve high accuracy, the commercial films correct for this through a dispersion of the yellow dye, which acts to correct fo...