Guillem Pratx

To quantify radiation induced glutathione (GSH) dynamics in A549 lung cancer cells using a ratiometric RealThiol (RT) probe and to assess microscopy and optical sensor platforms for real-time monitoring of redox responses following conventional and FLASH radi...

Diagnostic and Interventional Radiology Physics

Numerous radioligand therapy (RLT) agents are under various stages of development for treating late-stage cancers. We developed a computational methodology for identifying promising targets for RLT based on spatial transcriptomics analysis of tumor tissue.

Tumor hypoxia is a major driver of radiation resistance in solid tumors, yet its contribution to treatment response and metabolic reprogramming remains challenging to study using conventional models. This work proposes and validates a lung tumor-on-a-chip pla...