Author profile

Lisette LeMerise, MS

University of Wisconsin-Madison School of Medicine and Public Health and Waisman Center

Presenting AuthorPaper

A Multimodal Study of Biomarkers of Alzheimer’s Disease In Adults with Down Syndrome: Diffusion Tensor Imaging and Tau-PET

Individuals with Down syndrome (DS) are at high risk of developing Alzheimer's Disease, partially driven by trisomy 21-related overproduction of amyloid precursor protein and plaque (Aβ) development. Tau neurofibrillary tangles typically follow Aβ and obey si...

Proffered Program · Diagnostic and Interventional Radiology Physics

AuthorsPaper

Multi-Modal PET Imaging to Characterize the Relationship between Alzheimer’s Disease Pathology and Synaptic Density

Alzheimer’s disease (AD) is the most common form of dementia, exhibiting two characteristic brain neuropathologies - amyloid plaques (A) and neurofibrillary tau tangles (T) - hypothesized to disrupt neuronal function. Positron emission tomography (PET) is the...

Proffered Program · Radiopharmaceuticals, Theranostics, and Nuclear Medicine