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Author profile
Shannon E. Hartzell
Mayo Clinic
A Clinical Dose Prescription System for Proton Radiotherapy Based on Microdosimetric Spectral Information
Clinical proton dose prescription uses a fixed relative biological effectiveness (RBE) factor of 1.1 despite preclinical and clinical evidence that RBE varies with dose, radiation quality and tissue radiosensitivity, particularly near the distal edge of treat...
Poster Program · Therapy Physics
DIM-Free Monte-Carlo–Integrated Planning Optimization Using Randomized-Gradient-Free-Method (RGFM) for MCF Mkm Rbe Dose In Carbon Ion Therapy
The Mayo Clinic Florida microdosimetric kinetic model (MCF MKM) provides highly accurate relative biological effectiveness (RBE) calculations for carbon ion radiation therapy (CIRT), but its clinical use is limited by extreme memory and computational demands...
Poster Program · Therapy Physics
Preliminary Monte Carlo Benchmarking of the First U.S. Carbon TPS: Range, Voxel-Wise Differences, and Microdosimetry
To present preliminary validation results for the first carbon treatment planning system (TPS) in the United States and to benchmark its GPU Monte Carlo dose engine using depth-resolved dose and microdosimetric metrics.
Poster Program · Therapy Physics