Collin J. Harlan

To investigate the dependence of tumor metabolism on hyperpolarized (HP) pyruvate concentration, administration order, and time interval in repeated MRI measurements.

Hyperpolarized chemical exchange saturation transfer (HyperCEST) MRI using 129Xe gas enables detection of signal loss from perfluorooctyl bromide nanodroplets (PFOB NDs). We developed a kinetic model for 129Xe HyperCEST that enables quantitative analysis of t...